Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.52 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | CBX7 | O95931 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511316 | 0.89 | RECQL (0.71) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL942276 | 0.87 | CASP6 (0.51) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL6561310 | 0.85 | TIMP3 (0.62) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL30818027 | 0.85 | APEX1 (0.66) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL4649703 | 0.85 | APEX1 (0.66) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL9803468 | 0.85 | KMT2A (0.53) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL18136599 | 0.84 | TIMP3 (0.93) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL7653343 | 0.84 | APEX1 (0.71) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL11579638 | 0.82 | APEX1 (0.72) | TIMP3ALDH1A1MAPTPRMT1APEX1 | |
| SCHEMBL10413972 | 0.82 | TIMP3 (0.58) | TIMP3MEN1USP2RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134887-A | FIBER-REACTIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4066638-A | WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |