SCHEMBL11512295

SCHEMBL11512295

CS(=O)(=O)Nc1ccccc1.[NaH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.95
PGR P06401 1/20 0.64
NR3C2 P08235 5/20 0.62
PTGS2 P35354 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
HPGD P15428 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
HTT P42858 1/20 0.56
NPC1 O15118 1/20 0.55
AR P10275 1/20 0.55
RAB9A P51151 1/20 0.55
IL1RN P18510 1/20 0.54
ERAP1 Q9NZ08 1/20 0.54
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
KDM1A O60341 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56693 0.97 KEAP1 (1.00) KEAP1PGRNR3C2PTGS2CA1
Hydrochloric Acid SCHEMBL27365433 0.95 KEAP1 (0.95) KEAP1PGRNR3C2PTGS2CA1
Fluoride SCHEMBL28258745 0.95 KEAP1 (0.95) KEAP1PGRNR3C2PTGS2CA1
Hydrogen Sulfide SCHEMBL27698561 0.95 KEAP1 (0.95) KEAP1PGRNR3C2PTGS2CA1
SCHEMBL1358244 0.89 KEAP1 (0.83) KEAP1PGRNR3C2PTGS2CA1
SCHEMBL9479898 0.89 KEAP1 (0.83) KEAP1PGRNR3C2PTGS2CA1
Boric Acid SCHEMBL6312485 0.89 KEAP1 (0.83) KEAP1PGRNR3C2PTGS2CA1
SCHEMBL9387480 0.85 KEAP1 (0.76) KEAP1PGRNR3C2PTGS2CA1
Ethyl Chloride SCHEMBL27421992 0.85 KEAP1 (0.76) KEAP1PGRNR3C2PTGS2CA1
SCHEMBL27715693 0.85 KEAP1 (0.76) KEAP1PGRNR3C2PTGS2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-87108295-A New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method 1988-07-13 CN disclosed
US-4161524-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-07-17 US disclosed
US-4150155-A INSECTICIDES, NEMATOCIDES, MITICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1979-04-17 US disclosed
US-4134979-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed