Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.83 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56693 | 0.91 | KEAP1 (1.00) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27365433 | 0.89 | KEAP1 (0.95) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| SCHEMBL11512295 | 0.89 | KEAP1 (0.95) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL27698561 | 0.89 | KEAP1 (0.95) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| Fluoride SCHEMBL28258745 | 0.89 | KEAP1 (0.95) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| SCHEMBL1358244 | 0.87 | KEAP1 (0.83) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| SCHEMBL9479898 | 0.83 | KEAP1 (0.83) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| SCHEMBL28319287 | 0.80 | KEAP1 (0.70) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| SCHEMBL9387480 | 0.79 | KEAP1 (0.76) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 | |
| Ethyl Chloride SCHEMBL27421992 | 0.79 | KEAP1 (0.76) | KEAP1PGRNR3C2PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | KEAP1 3907/4885PGR 84/4885NR3C2 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.