Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512148 | 0.79 | HDAC1 (0.35) | HDAC1HTR2AHTR2CHTR2B | |
| SCHEMBL11512195 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL11512476 | 0.75 | HDAC1 (0.41) | HDAC1HTR2AHTR2CHTR2B | |
| SCHEMBL11512383 | 0.71 | OPRM1 (0.33) | HDAC1HTR2A | |
| SCHEMBL11511427 | 0.70 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL11514975 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11511237 | 0.65 | GAA (0.43) | HDAC1ALDH1A1 | |
| SCHEMBL11512169 | 0.65 | CETP (0.49) | ALDH1A1 | |
| SCHEMBL11512921 | 0.65 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL13900100 | 0.64 | HDAC1 (0.41) | HDAC1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |