Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512383 | 0.81 | OPRM1 (0.33) | HDAC1HTR2A | |
| SCHEMBL11512474 | 0.79 | HDAC1 (0.42) | HDAC1HTR2AHTR2CHTR2B | |
| SCHEMBL11511237 | 0.72 | GAA (0.43) | HDAC1GAA | |
| SCHEMBL11512195 | 0.71 | ALDH1A1 (0.39) | GAA | |
| SCHEMBL11511118 | 0.69 | NPC1 (0.37) | GAA | |
| SCHEMBL11510724 | 0.67 | GAA (0.40) | GAA | |
| SCHEMBL11511426 | 0.64 | GAA (0.45) | GAA | |
| SCHEMBL11511549 | 0.64 | GAA (0.45) | GAA | |
| SCHEMBL11511408 | 0.64 | SMN1; SMN2 (0.37) | HTR2A | |
| SCHEMBL11512475 | 0.62 | SMN1; SMN2 (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |