Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510987 | 0.80 | KMT2A (0.43) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11512183 | 0.76 | GAA (0.39) | ALDH1A1KMT2AMEN1CYP2C19MAPT | |
| SCHEMBL11510364 | 0.74 | CNR2 (0.35) | ADORA2AADORA2B | |
| SCHEMBL11511408 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11512383 | 0.73 | OPRM1 (0.33) | SMN1; SMN2 | |
| SCHEMBL11509890 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11512195 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL11512536 | 0.70 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6405301 | 0.68 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11509955 | 0.67 | TSHR (0.43) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |