Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11600531 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9768549 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9768566 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9768572 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1010632 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036650-A | SILVER SALT, SILVER HALIDE, REDUCING AGENT | CANON KABUSHIKI KAISHA (JA) | 1977-07-19 | — | — | US | claimed |
| US-4021250-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | claimed |
| CN-117511299-A | Preparation method of particle-free conductive ink | 昆明理工大学 | 2024-02-06 | — | — | CN | disclosed |
| US-20200047466-A1 | LAMINATED SAFETY GLASS | AGFA GRAPHICS NV (BE) | 2020-02-13 | — | — | US | disclosed |
| US-10549508-B2 | Laminated safety glass | AGFA NV (BE) | 2020-02-04 | — | — | US | disclosed |
| EP-2338939-B1 | CONDUCTIVE POLYMER SOLUTION, CONDUCTIVE COATING FILM AND INPUT DEVICE | SHINETSU POLYMER CO (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-20160303831-A1 | LAMINATED SAFETY GLASS | AGFA NV (BE) | 2016-10-20 | — | — | US | disclosed |
| EP-2400508-B1 | Conductive polymer solution, conductive coating film and input device | SHINETSU POLYMER CO (JP) | 2015-08-12 | — | — | EP | disclosed |
| EP-2883694-A1 | Laminated Safety Glass | AGFA GRAPHICS NV (BE) | 2015-06-17 | — | — | EP | disclosed |
| US-8877515-B2 | Measurement kit and an immunochromatography method | FUJIFILM CORPORATION (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8840812-B2 | Conductive polymer solution, conductive coating film, and input device | SHIN-ETSU POLYMER CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| US-4013473-A | THERMOGRAPHY, SUBSTITUTED PHENOL REDUCING AGENT | AGFA-GEVAERT N.V. (BE) | 1977-03-22 | — | — | US | disclosed |
| US-4009039-A | Heat developable light-sensitive oxazoline containing element | FUJI PHOTO FILM CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |
| US-4003749-A | Heat-developable light-sensitive materials using the reaction product of a organic silver salt an a N-halo-oxazolidinone | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-18 | — | — | US | disclosed |
| US-4002479-A | ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |
| US-3984249-A | TREATING WITH HYDROGEN | EASTMAN KODAK COMPANY (US) | 1976-10-05 | — | — | US | disclosed |
| US-3978335-A | ELECTROGRAPHIC RECORDING PROCESS | EASTMAN KODAK COMPANY (US) | 1976-08-31 | — | — | US | disclosed |
| US-3955982-A | HYDROCARBONS, HAL | EASTMAN KODAK COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3951660-A | HETEROCYCLIC TONER COMPOUND | AGFA-GEVAERT, A.G. (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3933508-A | ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |