Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.80 |
| ▸ | CA1 | P00915 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 3/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | CA3 | P07451 | 1/20 | 0.75 |
| ▸ | TYR | P14679 | 1/20 | 0.75 |
| ▸ | DRD1 | P21728 | 1/20 | 0.75 |
| ▸ | CA4 | P22748 | 1/20 | 0.75 |
| ▸ | CA6 | P23280 | 1/20 | 0.75 |
| ▸ | CA5A | P35218 | 1/20 | 0.75 |
| ▸ | CA7 | P43166 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.75 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.73 |
| ▸ | DAO | P14920 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5053781 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2841691 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17667155 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5014892 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5969822 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11409025-B2 | Functional sheet | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-08-09 | — | — | US | disclosed |
| US-20200174159-A1 | FUNCTIONAL SHEET | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3654078-A1 | FUNCTIONAL SHEET | Mitsubishi Gas Chemical Company, Inc. (JP) | 2020-05-20 | — | — | EP | disclosed |
| CN-108929440-A | Blocked copolyester, preparation method and barrier film, barrier bottle | 中国科学院宁波材料技术与工程研究所 | 2018-12-04 | — | — | CN | disclosed |
| WO-2013109865-A2 | MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS | GENOMATICA, INC. (US) | 2013-07-25 | — | — | WO | disclosed |
| US-8038954-B2 | CSF with low platinum/palladium ratios | BASF CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-20110243801-A1 | Passivation-Free Coating Process for a CSF | BASF CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| US-4632959-A | ADHESIVES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| US-4419507-A | BUTYLENE TEREPHTHALATE POLYMER | EASTMAN KODAK COMPANY (US) | 1983-12-06 | — | — | US | disclosed |