Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.80 |
| ▸ | CA1 | P00915 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 3/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | CA3 | P07451 | 1/20 | 0.75 |
| ▸ | TYR | P14679 | 1/20 | 0.75 |
| ▸ | DRD1 | P21728 | 1/20 | 0.75 |
| ▸ | CA4 | P22748 | 1/20 | 0.75 |
| ▸ | CA6 | P23280 | 1/20 | 0.75 |
| ▸ | CA5A | P35218 | 1/20 | 0.75 |
| ▸ | CA7 | P43166 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.75 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.73 |
| ▸ | DAO | P14920 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5053781 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1065024 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6664065 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10823257 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9484769 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 531349 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410620-B1 | — | — | None | — | — | US | claimed |
| US-6414058-B1 | — | — | None | — | — | US | claimed |
| US-6392091-B1 | — | — | None | — | — | US | claimed |
| CN-118835341-A | Preparation method and device of antibacterial polyester fiber | 江苏桐昆恒欣新材料有限公司 | 2024-10-25 | — | — | CN | claimed |
| WO-2024217684-A1 | USE OF A LIGNIN-BASED FILLER FOR PRODUCING A POLYMER COMPOSITION | UPM-KYMMENE CORPORATION (FI) | 2024-10-24 | — | — | WO | claimed |
| CN-118725324-A | Metal organic framework containing electron withdrawing group and preparation method and application thereof | 太原理工大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118725270-A | Polyarylate resin, and coating film and laminate containing the same | 尤尼吉可株式会社 | 2024-10-01 | — | — | CN | claimed |
| CN-118007265-B | High-elasticity cool polyester fiber and preparation process thereof | 江苏三联新材料股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-115803381-B | Aliphatic polyester resin composition and use thereof | 株式会社钟化 | 2024-09-24 | — | — | CN | claimed |
| US-12097688-B2 | Multilayer structure, method for producing same, packaging material and product including same, and protective sheet for electronic device | KURARAY CO., LTD. (JP) | 2024-09-24 | — | — | US | claimed |
| US-3932362-A | Amorphous polyamide of C-alkyl substituted diamine and terephthalic acid dialkyl ester having improved electrical creep resistance | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |
| US-3932326-A | POLYETHERS, AROMATIC CARBOXYLIC ACIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-01-13 | — | — | US | claimed |
| US-3932358-A | CROSSLINKING | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |
| US-3932351-A | Method of preparing phosphorus-bromine containing fire retardant polyester fibers | MONSANTO COMPANY (US) | 1976-01-13 | — | — | US | claimed |
| US-3931117-A | Coating powders for protective films based on ε-caprolactam-blocked isocyanates | COOK PAINT AND VARNISH COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-3931073-A | ADHESIVES, POLYESTER, HYDROCARBON | EASTMAN KODAK COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-3931305-A | Terephthalic acid recovery by continuous flash crystallization | STANDARD OIL COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-3931099-A | FIRE RETARDANT POLYESTER FIBERS | MONSANTO COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-3931418-A | Process for the production of insulating coatings on electrical conductors | DR. KURT HERBERTS & CO. GESELLSCHAFT MIT BESCHRANKTER HAFTUNG VORM. OTTO LOUIS HERBERTS (DT) | 1976-01-06 | — | — | US | claimed |
| US-3931210-A | Production of p-aminobenzoic acid | AKZO N.V. (NL) | 1976-01-06 | — | — | US | claimed |