SCHEMBL3661644

SCHEMBL3661644

COC(C)(OC)C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.60
SRC P12931 1/20 0.55
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CES2 O00748 4/20 0.44
LMNA P02545 2/20 0.43
F2 P00734 1/20 0.43
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
ELANE P08246 2/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KCNN4 O15554 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
POLB P06746 1/20 0.40
PRSS1 P07477 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332006 0.83 CES1 (0.60) CES1SRCTSHRALDH1A1TDP1
SCHEMBL10090157 0.83 CES1 (0.60) CES1SRCTSHRALDH1A1TDP1
SCHEMBL50469 0.81 CES1 (0.58) CES1SRCTSHRALDH1A1TDP1
SCHEMBL2150284 0.80 CES1 (0.62) CES1SRCTSHRALDH1A1TDP1
SCHEMBL28491178 0.80 CES1 (0.62) CES1SRCTSHRALDH1A1TDP1
SCHEMBL62160 0.80 CES1 (0.62) CES1SRCTSHRALDH1A1TDP1
SCHEMBL32101 0.79 CES1 (0.56) CES1SRCTSHRALDH1A1TDP1
SCHEMBL10944245 0.79 CES1 (0.47) CES1SRCTSHRALDH1A1TDP1
SCHEMBL11512906 0.79 CES1 (0.47) CES1SRCTSHRALDH1A1TDP1
SCHEMBL14430859 0.79 CES1 (0.56) CES1SRCTSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
EP-2219600-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2010-08-25 EP disclosed
WO-2009067095-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2009-05-28 WO disclosed
EP-1487770-B1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE COUNCIL SCIENT IND RES (IN) 2007-12-12 EP disclosed
EP-1786749-A1 ZEOLITE BASED CATALYTIC PROCESS FOR PREPARATION OF ACYLATED AROMATIC ETHERS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-05-23 EP disclosed
US-20070100157-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (AU) 2007-05-03 US disclosed
US-20060041171-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-02-23 US disclosed
WO-2006016197-A1 ZEOLITE BASED CATALYTIC PROCESS FOR PREPARATION OF ACYLATED AROMATIC ETHERS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-02-16 WO disclosed
US-6969778-B2 DDQ mediated one step dimerization of β-asarone or β-asarone rich Acorus calamus oil in the formation of novel neolignan COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-11-29 US disclosed
EP-1487770-A1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2004-12-22 EP disclosed
US-4857654-A Titanocenes and their use CIBA-GEIGY CORPORATION (US) 1989-08-15 US disclosed
EP-0318893-A2 Titanocenes, their use and N-substituted fluoroanilines CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
EP-0318894-A2 Titanocenes, their use and N-substituted pyrroles CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
EP-0269573-A2 Liquid photoinitiating mixture CIBA-GEIGY AG (CH) 1988-06-01 EP disclosed
EP-0256981-A2 Titanocenes and their use CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
US-4707432-A PROTECTIVE COATINGS, IMAGES CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
EP-0242330-A1 Liquid blend of photoinitiators CIBA-GEIGY AG (CH) 1987-10-21 EP disclosed
US-4533445-A ACRYLIC COATINGS FOR PRINTED CIRCUITS; ADHESION; DIELECTRICS SHIPLEY COMPANY INC. (US) 1985-08-06 US disclosed
US-4119640-A ACRYLIC OR METHACRYLIC ACID, DIEPOXIDES, INKS, HEAT OR RADIATION CURABLE COATINGS UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4100046-A Radiation polymerizable cycloalkenyl derivatives of acrylated epoxidized fatty oils or fatty acids UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070100157-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers KDM4E, ACE, CAT CES1 723/4885SRC 1453/4885TSHR 4861/4885
US-20060041171-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers KDM4E, ACE, CAT CES1 760/4885SRC 1450/4885TSHR 4864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.