Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513671 | 0.86 | LMNA (0.56) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11512534 | 0.82 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL3267203 | 0.82 | LMNA (0.51) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11513266 | 0.81 | LMNA (0.51) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11556911 | 0.80 | LMNA (0.53) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11515821 | 0.80 | ALDH1A1 (0.50) | LMNAGAAKDM4EHSD17B10TSHR | |
| SCHEMBL3267221 | 0.77 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11024710 | 0.75 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11512892 | 0.74 | PPID (0.39) | LMNANLRP3GAAKDM4EHSD17B10 | |
| SCHEMBL6627436 | 0.74 | LMNA (0.47) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |