Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 3/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511988 | 0.86 | PPID (0.38) | PPIDNLRP3PPIBPPIAPPIG | |
| SCHEMBL11134456 | 0.78 | SLC1A2 (0.34) | — | |
| SCHEMBL11512936 | 0.74 | LMNA (0.43) | PPIDNLRP3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11555149 | 0.68 | ELANE (0.45) | ALDH1A1LMNAALOX15KDM4EGAA | |
| SCHEMBL5184420 | 0.68 | GAA (0.53) | PPIDNLRP3PPIBPPIAPPIG | |
| SCHEMBL11513671 | 0.66 | LMNA (0.56) | PPIDNLRP3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8779653 | 0.66 | L3MBTL1 (0.38) | ALDH1A1LMNAALOX15KDM4EHSD17B10 | |
| SCHEMBL9586493 | 0.65 | ALDH1A1 (0.57) | PPIDNLRP3PPIBPPIAPPIG | |
| SCHEMBL19709868 | 0.65 | GAA (0.50) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL28735097 | 0.65 | GAA (0.50) | PPIDNLRP3PPIBPPIAPPIG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |