Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808441 | 1.00 | CASP1 (0.71) | CASP1TLR8TLR7HRH4NOS2 | |
| SCHEMBL1639952 | 0.93 | CASP1 (0.68) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL8141652 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL113501 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL379144 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL821896 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL821678 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL11408908 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL21327780 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR | |
| SCHEMBL9488393 | 0.91 | CASP1 (0.65) | CASP1TLR8TLR7HRH4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168364-A | Cyanamides of organic primary amines as epoxy curing agents | CIBA-GEIGY CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |