SCHEMBL9488393

SCHEMBL9488393

CCCCCCCCCCCCCCCCCc1nc(N)nc(N)n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.65
DHFR P00374 1/20 0.44
TLR8 Q9NR97 4/20 0.43
TLR7 Q9NYK1 2/20 0.43
ALDH1A1 P00352 3/20 0.42
KCNH2 Q12809 1/20 0.42
HRH4 Q9H3N8 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
ADORA1 P30542 1/20 0.39
HPGD P15428 2/20 0.38
PKM P14618 1/20 0.38
HTR2A P28223 1/20 0.38
TSHR P16473 2/20 0.37
GPR84 Q9NQS5 1/20 0.37
THRB P10828 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21327780 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL113501 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL821678 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL379144 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL8141652 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL10983992 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL11408908 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL821896 1.00 CASP1 (0.65) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL1639952 0.98 CASP1 (0.68) CASP1DHFRTLR8TLR7ALDH1A1
SCHEMBL2623157 0.95 CASP1 (0.58) CASP1DHFRTLR8TLR7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637574-B2 Coating composition KANSAI PAINT CO., LTD. (JP) 2026-05-26 US disclosed
CN-117794823-B Seamless can and coated metal sheet TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-05-26 CN disclosed
CN-117794822-B Seamless can and coated metal sheet TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-05-26 CN disclosed
US-12589910-B2 Method for producing drawn/ironed can and drawn/ironed can TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-03-31 US disclosed
US-20260035593-A1 AQUEOUS COATING MATERIAL COMPOSITION, METHOD FOR FORMING COATING FILM, AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO LTD (JP) 2026-02-05 US disclosed
US-12528619-B2 Drawn/ironed can and coated metal sheet for drawn/ironed cans TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-01-20 US disclosed
US-12503621-B2 Coating composition and method for forming multilayer coating film KANSAI PAINT CO., LTD. (JP) 2025-12-23 US disclosed
EP-4530725-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP (JP) 2025-12-03 EP disclosed
US-12466978-B2 Nanocellulose-containing aqueous coating composition for automotive exterior KANSAI PAINT CO., LTD. (JP) 2025-11-11 US disclosed
EP-4636045-A1 SPARKLING CLEAR COAT COMPOSITION AND MULTILAYER AUTOMOTIVE COATING INCLUDING THE SAME NIPPON PAINT AUTOMOTIVE EUROPE GmbH (DE) 2025-10-22 EP disclosed
CN-112543778-A One-component thermosetting epoxy resin composition SIKA技术股份公司 2021-03-23 CN disclosed
WO-2020035288-A1 ONE COMPONENT THERMOSETTING EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2020-02-20 WO disclosed
EP-3611202-A1 SINGLE-COMPONENT HEAT CURING EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2020-02-19 EP disclosed
EP-0395981-B1 EXPANDABLE STYRENE POLYMERS BASF Aktiengesellschaft (DE) 1993-01-13 EP disclosed
US-4973610-A CONTAINING BLOWING AGENT, BROMINE COMPOUND, AMMONIUM COMPOUND, AND AMINE BASF AKTIENGESELLSCHAFT (DE) 1990-11-27 US disclosed
EP-0395981-A1 Expandable styrene polymers BASF Aktiengesellschaft (DE) 1990-11-07 EP disclosed
EP-0003799-B1 FINELY DIVIDED EXPANDABLE STYRENE POLYMERS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-04 EP disclosed
US-4211688-A Process for dyeing high-molecular organic material in the melt CIBA-GEIGY CORPORATION (US) 1980-07-08 US disclosed
US-4192922-A Finely divided expandable styrene polymers HOECHST AKTIENGESELLSCHAFT (DE) 1980-03-11 US disclosed
US-3968298-A Process for imparting to natural keratin-containing material a permanent finish rendering the material resistant to damage by insects CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637574-B2 Coating composition ITGB3, ATG13, C9 CASP1 2940/4885DHFR 4885/4885TLR8 2551/4885
US-12589910-B2 Method for producing drawn/ironed can and drawn/ironed can TAS2R30, SLC11A2, TFRC CASP1 1971/4885DHFR 3116/4885TLR8 1287/4885
US-20260035593-A1 AQUEOUS COATING MATERIAL COMPOSITION, METHOD FOR FORMING COATING FILM, AND METHOD FOR FORMING MULTILAYER COATING FILM COL2A1, ALKBH2, C9 CASP1 2765/4885DHFR 4764/4885TLR8 2245/4885
US-12528619-B2 Drawn/ironed can and coated metal sheet for drawn/ironed cans ITK, SCO2, TMCO1 CASP1 1683/4885DHFR 4632/4885TLR8 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.