Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544240 | 0.86 | LMNA (0.47) | LMNAMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL11511602 | 0.86 | MAPT (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28837907 | 0.85 | MEN1 (0.49) | LMNAMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL11512000 | 0.83 | MAPT (0.62) | MEN1KMT2AHDAC8MAPTALDH1A1 | |
| SCHEMBL31478745 | 0.80 | MAPT (0.60) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11511974 | 0.79 | MAPT (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8355736 | 0.78 | MEN1 (0.51) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11510338 | 0.76 | MAPT (0.57) | LMNAMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL11513298 | 0.76 | MAPT (0.58) | MEN1KMT2AMAPTALDH1A1ALOX12 | |
| SCHEMBL11511610 | 0.75 | MRGPRX4 (0.52) | LMNAKMT2AHDAC1HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |