Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511427 | 0.81 | ALDH1A1 (0.43) | GAATSHRRECQLSMN1; SMN2TP53 | |
| SCHEMBL11510747 | 0.73 | ALDH1A1 (0.47) | GAATSHRRECQLSMN1; SMN2TP53 | |
| SCHEMBL11509890 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11509864 | 0.70 | HPGD (0.36) | GAARECQLSMN1; SMN2HTTHPGD | |
| SCHEMBL11509861 | 0.69 | HPGD (0.36) | GAARECQLSMN1; SMN2HTTHPGD | |
| SCHEMBL11510095 | 0.69 | HDAC2 (0.43) | GAATSHRSMN1; SMN2ALOX15HTT | |
| SCHEMBL11512018 | 0.69 | NPC1 (0.54) | GAARECQLSMN1; SMN2HTTHPGD | |
| SCHEMBL11512195 | 0.68 | ALDH1A1 (0.39) | GAATSHRSMN1; SMN2TP53ALOX15 | |
| SCHEMBL11511399 | 0.68 | GAA (0.55) | GAATSHRRECQLSMN1; SMN2TP53 | |
| SCHEMBL11511745 | 0.67 | IL15 (0.37) | GAATSHRSMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |