Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510033 | 0.78 | HDAC2 (0.67) | HDAC2PTK2HDAC1HDAC3HDAC8 | |
| SCHEMBL11511745 | 0.77 | IL15 (0.37) | HPGDHTTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL11509864 | 0.73 | HPGD (0.36) | HPGDHTTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL11509861 | 0.72 | HPGD (0.36) | HPGDHTTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL11510857 | 0.71 | HTT (0.52) | HDAC2PTK2HDAC1HDAC3HDAC8 | |
| SCHEMBL11512657 | 0.70 | RXRA (0.47) | HDAC2PTK2HDAC1HDAC3HDAC8 | |
| SCHEMBL11513288 | 0.69 | GAA (0.44) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11512018 | 0.69 | NPC1 (0.54) | HDAC2PTK2HDAC1HDAC3HDAC8 | |
| SCHEMBL9742985 | 0.67 | GPR84 (0.46) | SMN1; SMN2MEN1NPC1CYP1A2CYP2C19 | |
| SCHEMBL9743357 | 0.67 | GPR84 (0.46) | SMN1; SMN2MEN1NPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |