Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513293 | 1.00 | PDE4D (0.46) | PDE4DEPHX2PRKCAMEN1KMT2A | |
| SCHEMBL11514083 | 0.83 | PRKCA (0.43) | PDE4DPRKCAUSP2LMNA | |
| SCHEMBL14224913 | 0.80 | PDE4D (0.61) | PDE4DEPHX2PRKCAMEN1KMT2A | |
| SCHEMBL14224961 | 0.80 | PDE4D (0.61) | PDE4DEPHX2PRKCAMEN1KMT2A | |
| SCHEMBL11514906 | 0.78 | PDE4D (0.48) | PDE4DEPHX2PRKCA | |
| SCHEMBL11514911 | 0.78 | PDE4D (0.48) | PDE4DEPHX2PRKCA | |
| SCHEMBL11512202 | 0.78 | LMNA (0.34) | PDE4DEPHX2PRKCAUSP2LMNA | |
| SCHEMBL11512198 | 0.78 | LMNA (0.34) | PDE4DEPHX2PRKCAUSP2LMNA | |
| SCHEMBL11514096 | 0.78 | LMNA (0.34) | PDE4DEPHX2PRKCAUSP2LMNA | |
| SCHEMBL11593516 | 0.73 | PDE4D (0.37) | PDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155908-A | PSORIASIS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4128564-A | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins | MERCK & CO., INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4085125-A | 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes | MERCK & CO., INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4066675-A | PSORIASIS, THROMBOSIS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4018802-A | SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY | MERCK & CO., INC. (US) | 1977-04-19 | — | — | US | disclosed |