Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297570 | 0.73 | ADRA2A (0.34) | NISCHADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11197865 | 0.73 | AOC3 (0.39) | CYP2D6CYP2C9CYP1A2TAAR1 | |
| SCHEMBL28422866 | 0.66 | AOC3 (0.34) | CYP2D6CYP2C9CYP1A2TAAR1 | |
| Hydrochloric Acid SCHEMBL11098560 | 0.62 | MEN1 (0.40) | NISCHCYP2D6TSHRCYP2C9MAPK1 | |
| SCHEMBL28200069 | 0.61 | AOC3 (0.36) | CYP2D6CYP2C9CYP1A2TAAR1 | |
| SCHEMBL28268151 | 0.61 | AOC3 (0.36) | CYP2D6CYP2C9CYP1A2TAAR1 | |
| SCHEMBL4660214 | 0.61 | AOC3 (0.45) | MEN1KMT2AGAATAAR1 | |
| SCHEMBL2988656 | 0.61 | — | — | |
| SCHEMBL31469262 | 0.61 | AOC3 (0.45) | MEN1KMT2AGAATAAR1 | |
| SCHEMBL11266278 | 0.61 | NISCH (0.46) | NISCHCYP2D6TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117146-A | METHOD FOR TREATING DEPRESSION AND ANXIETY USING PHENYL HYDRAZO COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1978-09-26 | — | — | US | claimed |
| US-4150133-A | Method for treating depression and anxiety using phenyl hydrazo compounds | THE DOW CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4117146-A | METHOD FOR TREATING DEPRESSION AND ANXIETY USING PHENYL HYDRAZO COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1978-09-26 | — | — | US | disclosed |