SCHEMBL28200069

SCHEMBL28200069

NN(Br)c1ccccc1F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.36
ACHE P22303 1/20 0.35
TAAR1 Q96RJ0 3/20 0.34
NFE2L2 Q16236 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC6A3 Q01959 1/20 0.33
IDO1 P14902 2/20 0.32
KDM1A O60341 2/20 0.31
KDM1B Q8NB78 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11197865 0.79 AOC3 (0.39) AOC3ACHETAAR1NFE2L2CYP1A2
SCHEMBL7836478 0.79 ACHE (0.38) AOC3ACHETAAR1NFE2L2CYP1A2
SCHEMBL5730844 0.77 ACHE (0.36) ACHETAAR1NFE2L2CYP1A2CYP3A4
SCHEMBL4660214 0.75 AOC3 (0.45) AOC3ACHETAAR1NFE2L2ESR1
SCHEMBL31469262 0.75 AOC3 (0.45) AOC3ACHETAAR1NFE2L2ESR1
Hydrochloric Acid SCHEMBL4660143 0.73 AOC3 (0.44) AOC3ACHETAAR1NFE2L2IDO1
SCHEMBL20560208 0.72 ALDH1A1 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9SLC6A2
SCHEMBL28422866 0.71 AOC3 (0.34) AOC3ACHETAAR1NFE2L2CYP1A2
SCHEMBL163434 0.70 ACHE (0.39) AOC3ACHETAAR1NFE2L2CYP1A2
SCHEMBL29523028 0.70 ACHE (0.39) AOC3ACHETAAR1NFE2L2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed