Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA9 | P38646 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734170 | 0.81 | HSPA9 (0.49) | HSPA9HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL11810345 | 0.70 | RARB (0.44) | HSPA9KMT2AMEN1RARARARB | |
| SCHEMBL5928883 | 0.67 | HSD17B10 (0.58) | KMT2AMEN1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL587395 | 0.67 | MAPT (0.59) | HDAC2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27731438 | 0.67 | ALDH1A1 (0.52) | HDAC6KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8752430 | 0.66 | HPGD (0.55) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL1255273 | 0.66 | ALDH1A1 (0.60) | KMT2AALDH1A1MAPT | |
| SCHEMBL31456579 | 0.65 | RARB (0.53) | KMT2AMEN1ALDH1A1RARARARB | |
| SCHEMBL5540115 | 0.64 | AR (0.36) | HSPA9KMT2AMEN1RARARARB | |
| SCHEMBL9382451 | 0.63 | HDAC3 (0.65) | HSPA9HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |