SCHEMBL11513626

SCHEMBL11513626

CC(=O)O[Si](OC(C)=O)(OC(C)=O)C(F)(OC(C)C)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513621 0.75 TSHR (0.31) TSHR
SCHEMBL6654056 0.72 THRB (0.30)
SCHEMBL11198965 0.72 NPC1 (0.30) TSHR
SCHEMBL3142811 0.69 THRB (0.37)
SCHEMBL11146425 0.69 THRB (0.37)
SCHEMBL11651316 0.69
SCHEMBL5476313 0.67 TSHR (0.32) TSHR
SCHEMBL1053795 0.67 ALDH1A1 (0.33) TSHR
SCHEMBL3447715 0.67
SCHEMBL3445971 0.64 THRB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4167617-A Rapidly curable siloxane composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-09-11 US disclosed