SCHEMBL6654056

SCHEMBL6654056

CC(=O)O[Si](OC(C)=O)(OC(C)=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11146425 0.91 THRB (0.37) THRB
SCHEMBL3142811 0.91 THRB (0.37) THRB
SCHEMBL6656512 0.80
SCHEMBL7090687 0.77 THRB (0.30) THRB
SCHEMBL11513621 0.77 TSHR (0.31)
SCHEMBL1053795 0.75 ALDH1A1 (0.33)
SCHEMBL11198984 0.74
SCHEMBL11513626 0.72 TSHR (0.31)
SCHEMBL11198965 0.70 NPC1 (0.30)
SCHEMBL10879087 0.69 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124870-B1 CROSS-LINKABLE POLYMERS, METHOD FOR THE PRODUCTION THEREOF, AND SHAPED BODIES MADE OF CROSS-LINKED POLYMERS DEGUSSA (DE) 2004-07-14 EP disclosed
US-6528585-B1 Containing silane groups having hydrolyzable radical by free-radical initiated grafting with an olefinically unsaturated silane having hydrolyzable radical, grafting is carried out in presence of alkylsilane or fluoroalkylsilane DEGUSSA AG (DE) 2003-03-04 US disclosed
EP-1124870-A1 CROSS-LINKABLE POLYMERS, METHOD FOR THE PRODUCTION THEREOF, AND SHAPED BODIES MADE OF CROSS-LINKED POLYMERS Degussa Aktiengesellschaft (DE) 2001-08-22 EP disclosed
WO-2000023486-A1 CROSS-LINKABLE POLYMERS, METHOD FOR THE PRODUCTION THEREOF, AND SHAPED BODIES MADE OF CROSS-LINKED POLYMERS DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-04-27 WO disclosed