Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407916 | 0.96 | HSD11B1 (0.50) | HSD11B1PSMB5RARBTRPV1HPGD | |
| SCHEMBL29843944 | 0.92 | PTGS2 (0.50) | HSD11B1RARBTRPV1GPR84ALDH1A1 | |
| SCHEMBL27909193 | 0.92 | PTGS2 (0.50) | HSD11B1RARBTRPV1GPR84ALDH1A1 | |
| SCHEMBL25956744 | 0.91 | HSD11B1 (0.51) | HSD11B1PSMB5RARBTRPV1HPGD | |
| SCHEMBL28164034 | 0.90 | HSD11B1 (0.51) | HSD11B1RARBTRPV1GPR84ALDH1A1 | |
| SCHEMBL10599359 | 0.88 | PSMB5 (0.48) | HSD11B1PSMB5RARB | |
| SCHEMBL11515483 | 0.86 | PSMB5 (0.49) | HSD11B1PSMB5RARB | |
| SCHEMBL30500519 | 0.86 | PSMB5 (0.49) | HSD11B1PSMB5RARB | |
| SCHEMBL18419652 | 0.85 | RARB (0.50) | HSD11B1RARBHPGDNPC1MAPK1 | |
| SCHEMBL7120971 | 0.83 | HSD11B1 (0.44) | HSD11B1PSMB5RARBTRPV1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177156-A | SPECIALTY OILS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1979-12-04 | — | — | US | disclosed |
| US-4119555-A | COOLANTS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1978-10-10 | — | — | US | disclosed |