Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407916 | 0.87 | HSD11B1 (0.50) | HSD11B1TRPV1RARBPSMB5AKR1C2 | |
| SCHEMBL30585175 | 0.85 | RARB (0.44) | HSD11B1RARBAKR1C2AKR1C1HPGD | |
| SCHEMBL11513697 | 0.83 | HSD11B1 (0.50) | HSD11B1TRPV1RARBPSMB5AKR1C2 | |
| SCHEMBL2094991 | 0.82 | DHFR (0.47) | HSD11B1TRPV1ADORA3ESR1 | |
| SCHEMBL28164034 | 0.81 | HSD11B1 (0.51) | HSD11B1TRPV1RARBCHRNA7CHRNA10 | |
| SCHEMBL27747975 | 0.81 | TAAR1 (0.47) | HSD11B1RARBPSMB5ESR1ESR2 | |
| SCHEMBL18419652 | 0.81 | RARB (0.50) | HSD11B1RARBAKR1C2AKR1C1HPGD | |
| SCHEMBL27836083 | 0.80 | HSD11B1 (0.44) | HSD11B1RARBADORA3PTPN1 | |
| SCHEMBL25956744 | 0.79 | HSD11B1 (0.51) | HSD11B1TRPV1RARBPSMB5ADORA3 | |
| SCHEMBL29843944 | 0.76 | PTGS2 (0.50) | HSD11B1TRPV1RARBCHRNA7CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667830-B1 | Super-resolution microscope system and method for illumination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-12-23 | — | — | US | disclosed |