Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ATP4A | P20648 | 14/20 | 0.51 |
| ▸ | ATP4B | P51164 | 14/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514566 | 1.00 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4826178 | 0.84 | RAB9A (0.66) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4826174 | 0.84 | RAB9A (0.66) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL708951 | 0.84 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL708950 | 0.84 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL25491830 | 0.80 | KMT2A (0.61) | RAB9AMEN1KMT2AKDM4EMAPT | |
| SCHEMBL317883 | 0.79 | MEN1 (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL710009 | 0.79 | MEN1 (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12956185 | 0.78 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATP4A | |
| SCHEMBL11514571 | 0.77 | MAPT (0.50) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162254-A | Benzoxazole ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1979-07-24 | — | — | US | disclosed |
| US-4096115-A | Ultraviolet light stabilized polymers | EASTMAN KODAK COMPANY (US) | 1978-06-20 | — | — | US | disclosed |