SCHEMBL4826178

SCHEMBL4826178

COC(=O)c1ccc(C=Cc2nc3ccccc3o2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.66
NPC1 O15118 8/20 0.66
MEN1 O00255 6/20 0.66
KMT2A Q03164 6/20 0.66
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 3/20 0.61
HPGD P15428 3/20 0.61
CYP2D6 P10635 1/20 0.61
MAPT P10636 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HSD17B10 Q99714 1/20 0.61
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
HDAC8 Q9BY41 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4826174 1.00 RAB9A (0.66) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL9359757 0.85 MAPT (0.85) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL11341691 0.85 MAPT (0.85) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL11514575 0.84 NPC1 (0.57) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL11514566 0.84 NPC1 (0.57) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL710009 0.84 MEN1 (0.64) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL317883 0.84 MEN1 (0.64) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL11133760 0.82 PTPN1 (0.48) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL10491692 0.82 PTPN1 (0.48) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL12956185 0.80 NPC1 (0.67) RAB9ANPC1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210155879-A1 Cleaning Compositions RECKITT BENCKISER VANISH B.V. (NL) 2021-05-27 US disclosed
US-7438898-B1 Hair conditioning composition comprising carboxylic acid/carboxylate copolymer, and visible particle THE PROCTER & GAMBLE COMPANY (US) 2008-10-21 US disclosed
CN-1200674-C Hair conditioning composition comprising carboxylic acid/carboxylate copolymer and amphoteric conditioning agent P & G CO (US) 2005-05-11 CN disclosed
EP-1104278-B1 HAIR CONDITIONING COMPOSITION COMPRISING CARBOXYLIC ACID/CARBOXYLATE COPOLYMER, AND VISIBLE PARTICLE PROCTER & GAMBLE (US) 2004-11-24 EP disclosed
EP-1100435-B1 HAIR CONDITIONING COMPOSITION COMPRISING CARBOXYLIC ACID/CARBOXYLATE COPOLYMER AND AMPHOTERIC CONDITIONING AGENT PROCTER & GAMBLE (US) 2004-06-30 EP disclosed
CN-1147285-C Hair conditioning composition comprising carboxylic acid/carboxylate copolymer and visible particles 2004-04-28 CN disclosed
CN-1346258-A Transparent hair conditioning composition comprising breakable visible particle PROCTER & GAMBLE (US) 2002-04-24 CN disclosed
CN-1334717-A Hair conditioning composition comprising carboxylic acid/carboxylate copolymer and breakable visible particle PROCTER & GAMBLE (US) 2002-02-06 CN disclosed
CN-1334715-A Hair conditioning composition comprising breakable visible particle PROCTER & GAMBLE (US) 2002-02-06 CN disclosed
EP-1139984-A1 HAIR CONDITIONING COMPOSITION COMPRISING CARBOXYLIC ACID/CARBOXYLATE COPOLYMER AND BREAKABLE VISIBLE PARTICLE The Procter & Gamble Company (US) 2001-10-10 EP disclosed
WO-1999013828-A1 SHAMPOO COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND MILD SURFACTANT MATRIX THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013834-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND PERFUME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013844-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH PROVIDE UV PROTECTION THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013845-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH ALTER HAIR COLORS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013846-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013822-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND POLYMERIC SUSPENDING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013823-A2 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND HAIR CONDITIONING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013841-A1 HAIR STYLING COMPOSITIONS COMPRISING NONIONIC AND AMPHOTERIC OPTICAL BRIGHTENERS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013850-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND STABILITY ENHANCING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013849-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND HIGH MELTING POINT COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed