SCHEMBL708950

SCHEMBL708950

Cc1ccc(/C=C/c2nc3ccccc3o2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.63
RAB9A P51151 4/20 0.63
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
SNCA P37840 1/20 0.57
ATP4A P20648 13/20 0.55
ATP4B P51164 13/20 0.55
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
KDM4E B2RXH2 3/20 0.53
HPGD P15428 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708951 1.00 NPC1 (0.63) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL156861 0.86 SNCA (0.64) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL61657 0.86 SNCA (0.64) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL6421503 0.84 SNCA (0.64) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL6421501 0.84 SNCA (0.64) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL11514566 0.84 NPC1 (0.57) NPC1RAB9AMEN1KMT2AATP4A
SCHEMBL11514575 0.84 NPC1 (0.57) NPC1RAB9AMEN1KMT2AATP4A
SCHEMBL4007077 0.84 MEN1 (0.59) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL22360047 0.84 MEN1 (0.63) NPC1RAB9AMEN1KMT2ASNCA
SCHEMBL4007081 0.84 MEN1 (0.59) NPC1RAB9AMEN1KMT2ASNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180222236-A1 TRANSFER FILM, METHOD FOR MANUFACTURING FILM SENSOR, FILM SENSOR, FRONT PLATE-INTEGRATED SENSOR, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 US disclosed
US-9810984-B2 Photosensitive transfer material, pattern formation method, and etching method FUJIFILM CORPORATION (JP) 2017-11-07 US disclosed
US-20170199458-A1 PATTERN FORMING METHOD, ETCHING METHOD AND METHOD FOR PRODUCING CAPACITANCE-TYPE INPUT DEVICE FUJIFILM CORPORATION (JP) 2017-07-13 US disclosed
US-20160291468-A1 PHOTOSENSITIVE TRANSFER MATERIAL, PATTERN FORMATION METHOD, AND ETCHING METHOD FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20150219993-A1 PHOTOSENSITIVE TRANSFER MATERIAL, PATTERN FORMATION METHOD, AND ETCHING METHOD FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-8728708-B2 Photosensitive resin composition, oxime sulfonate compound, method for forming cured film, cured film, organic EL display device, and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8628907-B2 Positive photosensitive resin composition, method for forming cured film, cured film, organic el display device and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-01-14 US disclosed
US-20130171415-A1 PHOTOSENSITIVE RESIN COMPOSITION, OXIME SULFONATE COMPOUND, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-07-04 US disclosed
US-8124625-B2 enhancing the expression of apoAI; prevention or therapy of dislipidemia SHIONOGI & CO., LTD. (JP) 2012-02-28 US disclosed
US-20120045616-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-02-23 US disclosed
US-8053445-B2 Utilities of olefin derivatives SHIONOGI & CO., LTD. (JP) 2011-11-08 US disclosed
US-20090036457-A1 Utilities of olefin derivatives YAMAMORI TERUO 2009-02-05 US disclosed
US-20040242615-A1 Utilities of olefin derivatives SHIONOGI & CO., LTD. (JP) 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242615-A1 Utilities of olefin derivatives APOL1, NR1H2, APOB NPC1 19/4885RAB9A 4723/4885MEN1 3997/4885
US-20120045616-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE PELP1, EED, ARCN1 NPC1 3869/4885RAB9A 1367/4885MEN1 4568/4885
US-20130171415-A1 PHOTOSENSITIVE RESIN COMPOSITION, OXIME SULFONATE COMPOUND, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE OXER1, OXSR1, RAD51 NPC1 4551/4885RAB9A 2968/4885MEN1 4582/4885
US-20090036457-A1 Utilities of olefin derivatives APOL1, APOB, NR1H2 NPC1 48/4885RAB9A 4606/4885MEN1 3163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.