SCHEMBL11514923

SCHEMBL11514923

[O-][n+]1nc2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.37
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
PARP1 P09874 1/20 0.35
ACHE P22303 5/20 0.35
BCHE P06276 4/20 0.35
GRIN1 Q05586 4/20 0.35
GRIN2A Q12879 4/20 0.35
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
DYRK1A Q13627 1/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11519072 0.88 MAOA (0.41) ALDH1A1SMN1; SMN2HPGDLMNAMAPT
SCHEMBL11518738 0.78 HTT (0.39) ALDH1A1ACHEBCHEGRIN1GRIN2A
SCHEMBL11516553 0.74 ALDH1A1 (0.39) NR4A2ALDH1A1HPGDPARP1MAPK1
Hydrochloric Acid SCHEMBL11515870 0.72 CCNC (0.41) ALDH1A1SMN1; SMN2HPGDLMNAMAPT
SCHEMBL6690674 0.70 NR4A2 (0.35) NR4A2ALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL782083 0.70 ALDH1A1 (0.37) NR4A2ALDH1A1SMN1; SMN2HPGDMAPT
Hydrochloric Acid SCHEMBL11517969 0.69 CCNC (0.39) ALDH1A1SMN1; SMN2HPGDLMNAMAPT
SCHEMBL11517352 0.68 SMN1; SMN2 (0.52) NR4A2ALDH1A1SMN1; SMN2HPGDLMNA
SCHEMBL10962782 0.68 CYP2A6 (0.34) NR4A2ALDH1A1DYRK1A
SCHEMBL4275240 0.68 PIK3CG (0.47) NR4A2ALDH1A1LMNAMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed