Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517561 | 0.89 | GPR3 (0.61) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL38660517 | 0.89 | GPR3 (0.61) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL16795439 | 0.80 | MPO (0.45) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL31271850 | 0.80 | MPO (0.45) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL11517388 | 0.78 | TP53 (0.51) | SMN1; SMN2MAPTLMNAALDH1A1HPGD | |
| SCHEMBL6096600 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL30950666 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL10914614 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2MAPTLMNAF7F3 | |
| SCHEMBL6112367 | 0.74 | MAPT (0.41) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 | |
| SCHEMBL30950665 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTLMNAPIK3CGNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |