Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 7/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337548 | 0.83 | MAPK9 (0.51) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL11515131 | 0.80 | MAPK9 (0.55) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL11516409 | 0.77 | LOXL2 (0.57) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL7829657 | 0.75 | SMN1; SMN2 (0.51) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL7400010 | 0.74 | HPGD (0.59) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL21802341 | 0.74 | ALOX5 (0.57) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL28158591 | 0.73 | HPGD (0.58) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL21694384 | 0.73 | MAPK9 (0.48) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL11848949 | 0.73 | LOXL2 (0.49) | MAPK9MAPK10LOXL2HPGDALOX5 | |
| SCHEMBL7396493 | 0.72 | MAPK10 (0.64) | MAPK9MAPK10LOXL2HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146712-A | PROCESS FOR THE MANUFACTURE OF COUMARIN DYES | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
| US-4064136-A | FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE | CIBA-GEIGY AG (CH) | 1977-12-20 | — | — | US | disclosed |