SCHEMBL11515293

SCHEMBL11515293

COP(=O)(CC(=O)CC(C)C)OC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP2C19 P33261 1/20 0.36
ACHE P22303 1/20 0.36
CA2 P00918 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042103 0.81 POLB (0.34)
SCHEMBL9633869 0.80 BLM (0.41)
SCHEMBL3929515 0.79 CA1 (0.40)
SCHEMBL7948595 0.79 TSHR (0.34)
SCHEMBL9254795 0.79 TSHR (0.34)
SCHEMBL13908454 0.78 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL13908455 0.78 CA12 (0.31) ALDH1A1TDP1CA2MMP1MMP2
SCHEMBL7947601 0.76 PTPN1 (0.34)
SCHEMBL958471 0.76 FDPS (0.36) CA2
SCHEMBL9785162 0.76 FDPS (0.36) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4174458-A Novel analogues of prostanoic acids not occurring in nature HOECHST AKTIENGESELLSCHAFT (DE) 1979-11-13 US disclosed
US-4098815-A BRONCHODILATOR AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed