Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785162 | 0.87 | FDPS (0.36) | LMNACYP3A4 | |
| SCHEMBL958471 | 0.87 | FDPS (0.36) | LMNACYP3A4 | |
| SCHEMBL959451 | 0.84 | ACE2 (0.44) | — | |
| SCHEMBL7948595 | 0.83 | TSHR (0.34) | — | |
| SCHEMBL9254795 | 0.83 | TSHR (0.34) | — | |
| SCHEMBL7947601 | 0.81 | PTPN1 (0.34) | BLMPTPN1 | |
| SCHEMBL958472 | 0.81 | BLM (0.44) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL11515293 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL16682579 | 0.79 | KDM4C (0.36) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL6271680 | 0.78 | BLM (0.56) | BLMLMNAPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276124-B1 | PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0276124-A2 | Prostaglandin derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-07-27 | — | — | EP | disclosed |