Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519202 | 0.95 | ALDH1A1 (0.50) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL1615544 | 0.93 | ALDH1A1 (0.53) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL1397282 | 0.82 | EPHX1 (0.50) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL8114464 | 0.76 | ALDH1A1 (0.47) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL4379254 | 0.76 | EPHX1 (0.62) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL20693658 | 0.75 | — | — | |
| SCHEMBL13767350 | 0.75 | SHBG (0.48) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL23331653 | 0.73 | ALDH1A1 (0.44) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL16281688 | 0.73 | ALDH1A1 (0.44) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL17163913 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154931-A | Process for the preparation of cyclic ureas | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | disclosed |