Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519430 | 0.89 | AOC3 (0.44) | AOC3ALDH1A1HPGDADORA2BSRC | |
| SCHEMBL11516126 | 0.87 | AOC3 (0.37) | AOC3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL11515027 | 0.83 | AOC3 (0.47) | AOC3KDM4ESMN1; SMN2 | |
| SCHEMBL11518652 | 0.79 | AOC3 (0.40) | AOC3ALDH1A1HPGDMEN1HTT | |
| SCHEMBL11516165 | 0.74 | AOC3 (0.43) | AOC3ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL11516529 | 0.72 | AOC3 (0.51) | AOC3MEN1KMT2A | |
| SCHEMBL11515890 | 0.71 | AOC3 (0.39) | AOC3ALDH1A1KDM4E | |
| SCHEMBL11517973 | 0.70 | AOC3 (0.46) | AOC3ALDH1A1MAPTNPSR1 | |
| SCHEMBL11515083 | 0.69 | RAB9A (0.44) | AOC3ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL11517524 | 0.69 | TRPM8 (0.45) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |