Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11517181 | 0.99 | HRH3 (0.39) | HRH3CYP3A4ATMSMN1; SMN2PKM | |
| SCHEMBL11516079 | 0.85 | LMNA (0.45) | HRH3ATMSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL11515494 | 0.85 | BAZ2B (0.43) | HRH3 | |
| Hydrochloric Acid SCHEMBL11516834 | 0.84 | LMNA (0.44) | ATMSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL12662820 | 0.80 | BAZ2B (0.43) | MAPK1 | |
| SCHEMBL11516180 | 0.79 | POLB (0.51) | ATMSMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL15490068 | 0.78 | POLB (0.37) | ATM | |
| SCHEMBL11516638 | 0.78 | KDM4E (0.45) | ATMMAPK1HSD17B10 | |
| SCHEMBL1994788 | 0.78 | NAMPT (0.38) | HRH3MAPK1 | |
| SCHEMBL15492450 | 0.76 | CREBBP (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |