Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.43 |
| ▸ | HPGDS | O60760 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516180 | 0.95 | POLB (0.51) | KDM4EALDH1A1MAPTMAPK1CASP1 | |
| SCHEMBL11518328 | 0.84 | MAPT (0.45) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL11515494 | 0.82 | BAZ2B (0.43) | POLB | |
| SCHEMBL11517624 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTPOLBHTT | |
| SCHEMBL11515869 | 0.78 | HRH3 (0.39) | MAPK1ATMHSD17B10 | |
| SCHEMBL1994788 | 0.78 | NAMPT (0.38) | KDM4EMAPK1POLBENPP2 | |
| SCHEMBL11515001 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTPOLBHTT | |
| Hydrochloric Acid SCHEMBL11517181 | 0.77 | HRH3 (0.39) | MAPK1ATMHSD17B10 | |
| SCHEMBL31595886 | 0.77 | NAMPT (0.37) | KDM4EMAPK1POLBENPP2 | |
| SCHEMBL12662820 | 0.77 | BAZ2B (0.43) | MAPTMAPK1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |