Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517479 | 0.84 | CYP3A4 (0.55) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11861828 | 0.82 | SHBG (0.58) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11861831 | 0.82 | SHBG (0.58) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11860406 | 0.79 | PGR (0.55) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11517786 | 0.78 | ESR1 (0.55) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL29595094 | 0.76 | PGR (0.67) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11858237 | 0.73 | PGR (0.71) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL30140942 | 0.73 | PGR (0.71) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL11858232 | 0.73 | PGR (0.71) | SHBGLMNAPGRSLC6A4CYP3A4 | |
| SCHEMBL12178072 | 0.72 | SHBG (0.46) | SHBGLMNAPGRSLC6A4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150126-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS AND ANIBODY INHIBITORS | AKTIEBOLAGET LEO (SE) | 1979-04-17 | — | — | US | disclosed |