Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | ESR1 | P03372 | 6/20 | 0.67 |
| ▸ | SHBG | P04278 | 5/20 | 0.67 |
| ▸ | AR | P10275 | 5/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levonorgestrel SCHEMBL14360765 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Norgestrel SCHEMBL4319113 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL3916570 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL825664 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL27597 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL691861 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL22364344 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL21741985 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Levonorgestrel SCHEMBL20927506 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 | |
| Norgestrel SCHEMBL37118 | 0.80 | PGR (1.00) | PGRLMNASLC6A4CYP3A4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766400-B2 | Biodegradable contraceptive implants | YALE UNIVERSITY (US) | 2023-09-26 | — | — | US | claimed |
| US-20250248928-A1 | NANOPARTICLES AND NANOPARTICLE-RELEASING VAGINAL RINGS | YALE UNIVERSITY | 2025-08-07 | — | — | US | disclosed |
| EP-4507675-A1 | NANOPARTICLES AND NANOPARTICLE-RELEASING VAGINAL RINGS | Yale University (US) | 2025-02-19 | — | — | EP | disclosed |
| CN-118317794-A | Composition for treating dysmenorrhea | 戴尔生物科学公司 | 2024-07-09 | — | — | CN | disclosed |
| US-11814408-B2 | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof | NICOX OPHTHALMICS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| WO-2023200974-A1 | NANOPARTICLES AND NANOPARTICLE-RELEASING VAGINAL RINGS | YALE UNIVERSITY (US) | 2023-10-19 | — | — | WO | disclosed |
| US-11766400-B2 | Biodegradable contraceptive implants | YALE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11766400-B2 | Biodegradable contraceptive implants | LHCGR, PGF, SHBG | PGR 4/4885LMNA 399/4885SLC6A4 4788/4885 |
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | LRBA, IAPP, FABP4 | PGR 3717/4885LMNA 1305/4885SLC6A4 3581/4885 |
| US-20250248928-A1 | NANOPARTICLES AND NANOPARTICLE-RELEASING VAGINAL RINGS | MUC1, CD63, EPCAM | PGR 4/4885LMNA 2222/4885SLC6A4 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.