SCHEMBL1151660

SCHEMBL1151660

NC(=NO)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
KMT2A Q03164 2/20 0.62
GFER P55789 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
PARP10 Q53GL7 4/20 0.60
GAA P10253 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
SRD5A2 P31213 2/20 0.48
LTA4H P09960 2/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
MAOA P21397 1/20 0.48
TSHR P16473 1/20 0.48
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
F2 P00734 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3064538 1.00 LMNA (0.62) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3052608 0.82 LMNA (0.65) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3052606 0.82 LMNA (0.65) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL16856039 0.82 KMT2A (0.60) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL20263737 0.82 KMT2A (0.60) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3047604 0.81 CYP19A1 (0.54) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3047598 0.81 CYP19A1 (0.54) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3064530 0.81 LMNA (0.58) LMNAKMT2AGFERL3MBTL1PARP10
SCHEMBL3064531 0.81 LMNA (0.58) LMNAKMT2AGFERL3MBTL1PARP10
Benzamidoxime SCHEMBL30242 0.80 KMT2A (0.58) KMT2AL3MBTL1GAARAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US disclosed
US-20230091947-A1 ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS WAYNE STATE UNIVERSITY (US) 2023-03-23 US disclosed
US-20210207274-A1 ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS WAYNE STATE UNIVERSITY (US) 2021-07-08 US disclosed
US-9045442-B2 Antibacterial compounds and methods of using same UNIVERSITY OF NOTRE DAME DU LAC (US) 2015-06-02 US disclosed
US-20150133495-A1 Substituted Acyloxyamidines as HCV NS3/4A Inhibitors VIROCURA THERAPEUTICS INC (CA) 2015-05-14 US disclosed
US-8877515-B2 Measurement kit and an immunochromatography method FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed
US-8835182-B2 Immunochromatographic device FUJIFILM CORPORATION (JP) 2014-09-16 US disclosed
EP-2042871-B1 Method for mixing two or more types of liquids in porous carrier FUJIFILM CORP (JP) 2013-07-10 EP disclosed
US-20130137190-A1 IMMUNOCHROMATOGRAPHIC DEVICE FUJIFILM CORPORATION (JP) 2013-05-30 US disclosed
US-8383422-B2 Immunochromatographic device FUJIFILM CORPORATION (JP) 2013-02-26 US disclosed
US-5196301-A 3-substituted-5-alkylthio-1,2,4-triazoles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-23 US disclosed
US-5175081-A Post-processsing stabilization of photothermographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-12-29 US disclosed
US-5158866-A POST-PROCESSING STABILIZATION OF PHOTOTHERMOGRAPHIC EMULSIONS WITH AMIDO COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-27 US disclosed
US-5149620-A 5-mercapto-1,2,4-triazole derivatives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-22 US disclosed
EP-0480568-A2 Post-processing stabilization of photothermographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-15 EP disclosed
EP-0473351-A2 Post-processing stabilization of photothermographic emulsions with amido compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-04 EP disclosed
WO-1992002852-A1 POST-PROCESSING STABILIZED PHOTOTHERMOGRAPHIC EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-20 WO disclosed
WO-1992002853-A1 POST-PROCESSING STABILIZATION OF PHOTOTHERMOGRAPHIC EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-20 WO disclosed
US-4923792-A BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-08 US disclosed
US-4883747-A LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133495-A1 Substituted Acyloxyamidines as HCV NS3/4A Inhibitors EIF2AK2, GTF3C4, GTF3C1 LMNA 4687/4885KMT2A 1919/4885GFER 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.