Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064531 | 1.00 | LMNA (0.58) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL282989 | 0.82 | KDM1A (0.53) | LMNAKMT2ARAB9AGAANPC1 | |
| SCHEMBL641911 | 0.82 | KDM1A (0.53) | LMNAKMT2ARAB9AGAANPC1 | |
| SCHEMBL282987 | 0.82 | KDM1A (0.53) | LMNAKMT2ARAB9AGAANPC1 | |
| SCHEMBL3047604 | 0.82 | CYP19A1 (0.54) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL3047598 | 0.82 | CYP19A1 (0.54) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL1151660 | 0.81 | LMNA (0.62) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL3064538 | 0.81 | LMNA (0.62) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL16856039 | 0.79 | KMT2A (0.60) | LMNAKMT2AGFERL3MBTL1RAB9A | |
| SCHEMBL3052606 | 0.79 | LMNA (0.65) | LMNAKMT2AGFERL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045442-B2 | Antibacterial compounds and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045442-B2 | Antibacterial compounds and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045442-B2 | Antibacterial compounds and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20100261673-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100261673-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100261673-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2010-10-14 | — | — | US | disclosed |
| WO-2009082398-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009082398-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009041972-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009041972-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261673-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME | SPOUT1, MRPL21, NPEPPS | LMNA 3491/4885KMT2A 4009/4885GFER 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.