SCHEMBL11516626

SCHEMBL11516626

Cc1nc(-c2cc[c]cc2)c(-c2cc[c]cc2)n1C

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.36
ALOX5 P09917 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CNR1 P21554 6/20 0.35
MAPK14 Q16539 5/20 0.35
MAPK13 O15264 3/20 0.35
MAPK12 P53778 3/20 0.35
MAPK11 Q15759 3/20 0.35
GCGR P47871 2/20 0.35
CDK9 P50750 1/20 0.34
DYRK1A Q13627 1/20 0.34
KDM1A O60341 1/20 0.34
FAAH O00519 2/20 0.33
CSNK1D P48730 1/20 0.33
PTGER1 P34995 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516631 0.81 KDM4E (0.51) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL15987599 0.80 PTGER1 (0.49) ALOX5KDM4EALDH1A1HPGDTSHR
SCHEMBL9961397 0.74 NSD3 (0.55) ALOX5KDM4EALDH1A1HPGDTSHR
SCHEMBL11515628 0.72 MEN1 (0.35) ALOX5KDM4EALDH1A1HPGDHSD17B10
SCHEMBL11516035 0.67 HSD11B1 (0.44) ALDH1A1HPGDTSHR
SCHEMBL822678 0.65 PTGER1 (0.56) ALOX5KDM4EALDH1A1HPGDTSHR
SCHEMBL714363 0.64 MEN1 (0.68) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL715301 0.64 CYP1A2 (0.50) KDM4EALDH1A1
SCHEMBL4084116 0.63 CNR1 (0.48) KDM4EALDH1A1HPGDCNR1KDM1A
SCHEMBL12926029 0.63 NTRK1 (0.43) KDM4EALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed