SCHEMBL11516631

SCHEMBL11516631

Cc1nc(-c2ccccc2)c(-c2ccccc2)n1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 3/20 0.51
HPGD P15428 2/20 0.51
TSHR P16473 1/20 0.51
CNR1 P21554 3/20 0.48
GAA P10253 1/20 0.46
FAAH O00519 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTGER1 P34995 1/20 0.46
MAPT P10636 2/20 0.43
CASP1 P29466 2/20 0.43
PDE10A Q9Y233 1/20 0.43
NTRK1 P04629 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
BRCA1 P38398 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9961397 0.91 NSD3 (0.55) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL822678 0.84 PTGER1 (0.56) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL12926029 0.82 NTRK1 (0.43) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL11516626 0.81 TGFBR1 (0.36) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL4075651 0.78 KDM4E (0.50) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL9725937 0.78 HPGD (0.50) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL27217113 0.78 NPC1 (0.39) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15716944 0.78 ALDH1A1 (0.50) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL11978720 0.77 BCHE (0.55) KDM4EHSD17B10TSHRGAAFAAH
SCHEMBL18152791 0.77 FABP4 (0.46) KDM4EALDH1A1HSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478750-A1 CROSS-LINKED HIGH STABLE ANION EXCHANGE BLEND MEMBRANES WITH POLYETHYLENEGLYCOLS AS HYDROPHILIC MEMBRANE PHASE Between Lizenz GmbH (DE) 2019-05-08 EP claimed
US-20220212183-A1 CROSS-LINKED HIGH STABLE ANION EXCHANGE BLEND MEMBRANES WITH POLYETHYLENEGLYCOLS AS HYDROPHILIC MEMBRANE PHASE HAERING THOMAS (DE) 2022-07-07 US disclosed
EP-3478750-A1 CROSS-LINKED HIGH STABLE ANION EXCHANGE BLEND MEMBRANES WITH POLYETHYLENEGLYCOLS AS HYDROPHILIC MEMBRANE PHASE Between Lizenz GmbH (DE) 2019-05-08 EP disclosed
US-8852757-B2 Organic electroluminescence element, lighting device and display device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-10-07 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20100045171-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-02-25 US disclosed
US-7429579-B2 Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents) SMITHKLINE BEECHAM, PLC (GB) 2008-09-30 US disclosed
US-7429579-B2 Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents) SMITHKLINE BEECHAM, PLC (GB) 2008-09-30 US disclosed
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL KDM4E 367/4885ALDH1A1 54/4885HSD17B10 1931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.