Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515001 | 0.99 | ALDH1A1 (0.53) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL11518328 | 0.95 | MAPT (0.45) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL11516180 | 0.85 | POLB (0.51) | ALDH1A1HTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL11516079 | 0.80 | LMNA (0.45) | ALDH1A1LMNASMN1; SMN2MAPTHRH4 | |
| SCHEMBL11515901 | 0.80 | MEN1 (0.43) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11516834 | 0.79 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11516638 | 0.79 | KDM4E (0.45) | ALDH1A1HTTMAPTKDM4EPOLB | |
| SCHEMBL11514216 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL11514380 | 0.74 | KMT2A (0.48) | ALDH1A1LMNASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL11518462 | 0.73 | MAPT (0.43) | ALDH1A1LMNASMN1; SMN2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |