Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476351 | 0.98 | KEAP1 (0.70) | KEAP1NFE2L2PTGS1PTGS2L3MBTL1 | |
| SCHEMBL29904739 | 0.84 | KEAP1 (0.65) | KEAP1NFE2L2PTGS1PTGS2L3MBTL1 | |
| SCHEMBL2068498 | 0.84 | KEAP1 (0.65) | KEAP1NFE2L2PTGS1PTGS2L3MBTL1 | |
| SCHEMBL11709570 | 0.82 | ALDH1A1 (0.56) | KEAP1NFE2L2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL15108064 | 0.81 | KEAP1 (1.00) | KEAP1NFE2L2PTGS1PTGS2L3MBTL1 | |
| SCHEMBL21811382 | 0.81 | ALDH1A1 (0.51) | KEAP1NFE2L2PTGS1PTGS2ALDH1A1 | |
| SCHEMBL6357772 | 0.78 | KEAP1 (0.57) | KEAP1NFE2L2PTGS1PTGS2L3MBTL1 | |
| SCHEMBL28645207 | 0.78 | ALDH1A1 (0.53) | KEAP1NFE2L2ALDH1A1MAPTHTT | |
| SCHEMBL2004599 | 0.78 | ALDH1A1 (0.53) | KEAP1NFE2L2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL29812756 | 0.78 | ALDH1A1 (0.53) | KEAP1NFE2L2L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161524-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-4150155-A | INSECTICIDES, NEMATOCIDES, MITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1979-04-17 | — | — | US | disclosed |
| US-4134979-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |