SCHEMBL2004599

SCHEMBL2004599

Cc1ccccc1NS(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
HPGD P15428 3/20 0.50
KEAP1 Q14145 2/20 0.50
TSHR P16473 1/20 0.49
THRB P10828 1/20 0.49
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
POLB P06746 2/20 0.47
NFE2L2 Q16236 1/20 0.47
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29812756 1.00 ALDH1A1 (0.53) ALDH1A1NPC1RAB9AHPGDKEAP1
Hydrochloric Acid SCHEMBL28137065 0.98 ALDH1A1 (0.51) ALDH1A1NPC1RAB9AHPGDKEAP1
SCHEMBL6684548 0.84 TSHR (0.42) KEAP1TSHRGAAMAPTHTT
SCHEMBL27506946 0.83 ALDH1A1 (0.50) ALDH1A1NPC1RAB9AHPGDKEAP1
SCHEMBL11672581 0.83 KEAP1 (0.69) ALDH1A1NPC1RAB9AKEAP1TSHR
SCHEMBL11709570 0.82 ALDH1A1 (0.56) ALDH1A1NPC1RAB9AHPGDKEAP1
SCHEMBL9686067 0.80 KEAP1 (0.46) ALDH1A1NPC1RAB9AHPGDKEAP1
SCHEMBL1476351 0.80 KEAP1 (0.70) ALDH1A1NPC1RAB9AKEAP1TSHR
SCHEMBL11516751 0.78 KEAP1 (0.68) ALDH1A1NPC1RAB9AKEAP1TSHR
SCHEMBL28645207 0.78 ALDH1A1 (0.53) ALDH1A1NPC1RAB9AHPGDKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452960-B1 Method for preparing hexamethyl cyclotrisilazane SHINETSU CHEMICAL CO (JP) 1995-06-28 EP claimed
US-5075474-A Catalytic heating of dimethylsilazane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-12-24 US claimed
EP-0452960-A2 Method for preparing hexamethyl cyclotrisilazane Shin-Etsu Chemical Co., Ltd. (JP) 1991-10-23 EP claimed
EP-0099954-B1 LIQUEFACTANTS FOR HYDRAULIC BINDERS CHRYSO SA - Ets. de TOULOUSE (FR) 1986-10-22 EP claimed
US-4518725-A Fluidizing agents for hydraulic bonding materials; hydraulic bonding materials containing said fluidizing agents; method of making and using same CHRYSO S.A. (FR) 1985-05-21 US claimed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 US claimed
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD KYOTO UNIVERSITY (JP) 2024-05-23 US disclosed
EP-4306927-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD Kyoto University (JP) 2024-01-17 EP disclosed
WO-2023188655-A1 STRENGTH ENHANCER FOR HYDRAULIC COMPOSITION, ADMIXTURE FOR HYDRAULIC COMPOSITION, HYDRAULIC COMPOSITION, AND HYDRAULIC COMPOSITION CURED PRODUCT 竹本油脂株式会社 2023-10-05 WO disclosed
CN-114450351-A Thermosetting resin composition, thermosetting resin sheet, electronic component, and electronic device 东丽株式会社 2022-05-06 CN disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-102718665-B Insecticide for agricultural or horticultural use prepare intermediate MITSUI CHEMICAL INDUSTRY CO., LTD. (JP) 2015-09-16 CN disclosed
CN-104892431-A Insecticide for agricultural or horticultural use and method of use thereof MITSUI CHEMICALS INC 2015-09-09 CN disclosed
EP-0048538-A1 Azo dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-31 EP disclosed
US-4285864-A Disulfonic phenyl-azo-naphthyl-azo-phenyl alkoxy dyes for polyamides CROMPTON & KNOWLES CORPORATION (US) 1981-08-25 US disclosed
US-4085057-A Toner for electrostatic printing of sheet like materials containing triazine antistatic agent KANEBO LTD. (JA) 1978-04-18 US disclosed
US-4016182-A Process for the production of aminoanthraquinone compounds SANDOZ LTD. (CH) 1977-04-05 US disclosed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 US disclosed
US-3951965-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed
US-3932376-A DYEING POLYAMIDES CROMPTON & KNOWLES CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD TST, TTR, ALB ALDH1A1 3942/4885NPC1 3784/4885RAB9A 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.