Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151708 | 0.80 | MEN1 (0.57) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL14921484 | 0.80 | MEN1 (0.63) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL1193541 | 0.77 | BCL6 (0.58) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL26418166 | 0.76 | NPC1 (0.58) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL11225942 | 0.73 | MEN1 (0.48) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL14445556 | 0.73 | LMNA (0.69) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL633400 | 0.70 | MEN1 (0.77) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL796546 | 0.69 | NPC1 (0.50) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL7226196 | 0.69 | MAPT (0.67) | GAAMEN1MAPTKMT2AKDM4E | |
| Diphenylamine SCHEMBL27258248 | 0.68 | HSD17B10 (0.67) | GAAMEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |