SCHEMBL11517121

SCHEMBL11517121

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSK P43235 13/20 0.63
CTSL P07711 5/20 0.59
CTSS P25774 3/20 0.59
CTSB P07858 3/20 0.59
CAPN1 P07384 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11822319 0.87 TACR1 (0.54) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL7273944 0.87 TACR1 (0.54) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL10974305 0.86 KDM4E (0.47) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL9320196 0.84 KDM4E (0.48) CTSKCTSLCTSSCTSB
SCHEMBL11795571 0.84 KDM4E (0.52) CTSKCTSLCTSSCTSB
SCHEMBL5689816 0.83 CTSL (0.53) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL11796386 0.83 CTSL (0.53) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL16272916 0.82 CTSK (0.76) CTSKCTSLCTSSCTSB
SCHEMBL5689754 0.81 CTSL (0.57) CTSKCTSLCTSSCTSB
SCHEMBL5689757 0.81 CTSL (0.57) CTSKCTSLCTSSCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159980-A Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1979-07-03 US disclosed
US-4159980-A Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1979-07-03 US disclosed
US-3835108-A PROCESS FOR PREPARING THE RELEASING HORMONE OF LUTEINIZING HORMONE(LH)AND OF FOLLICLE STIMULATING HORMONE(FSH),SALTS AND COMPOSITIONS THEREOF,AND INTERMEDIATES THEREFOR AMERICAN HOME PROD 1974-09-10 US disclosed