Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822319 | 1.00 | TACR1 (0.54) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL5689816 | 0.96 | CTSL (0.53) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL11796386 | 0.96 | CTSL (0.53) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL11658723 | 0.93 | ITGB3 (0.53) | CTSSCTSKALDH1A1KDM4EHPGD | |
| SCHEMBL7465441 | 0.89 | NOS2 (0.51) | ALDH1A1ALOX15 | |
| SCHEMBL9320196 | 0.87 | KDM4E (0.48) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL11517121 | 0.87 | CTSK (0.63) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL11686578 | 0.85 | EPHX2 (0.58) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL11694974 | 0.85 | NMBR (0.64) | TACR1HTT | |
| SCHEMBL10974305 | 0.83 | KDM4E (0.47) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185390-B1 | TRIPEPTIDYL-ARGININALDEHYDE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS THEREOF, AS WELL AS N-(MONOALKYL) AND N,N-DI-(ALKYL)-XXX-L-PROLINE DIPEPTIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-10-02 | — | — | EP | disclosed |
| US-4703036-A | ANTICOAGULANTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-10-27 | — | — | US | disclosed |
| EP-0185390-A2 | Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as N-(monoalkyl) and N,N-di-(alkyl)-Xxx-L-proline dipeptide | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-06-25 | — | — | EP | disclosed |