Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747229 | 0.90 | ESR1 (0.69) | LMNAESR1SHBGESR2SMN1; SMN2 | |
| SCHEMBL22887515 | 0.85 | MRGPRX4 (0.50) | LMNAESR1SHBGESR2NPC1 | |
| SCHEMBL146018 | 0.83 | ESR1 (0.80) | LMNAESR1SHBGESR2SMN1; SMN2 | |
| SCHEMBL30497946 | 0.83 | ESR1 (0.80) | LMNAESR1SHBGESR2SMN1; SMN2 | |
| SCHEMBL30394799 | 0.80 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL1515738 | 0.80 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9061935 | 0.79 | ESR1 (0.59) | LMNAESR1SHBGESR2SMN1; SMN2 | |
| Phenylacetic Acid SCHEMBL9106985 | 0.78 | AKR1B1 (0.59) | LMNAESR2HTTGAAFNTA | |
| SCHEMBL2384382 | 0.78 | LMNA (0.61) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL7253586 | 0.77 | HSP90AB1 (0.69) | LMNAESR1SHBGESR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179436-A | DYEING POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |